Man's Best Friend (1993)
Man's Best Friend is a 1993 American black comedy horror film, written and directed by John Lafia. It stars Ally Sheedy as a TV personality who adopts a genetically altered Tibetan Mastiff, and Lance Henriksen as a mad scientist who tries to track down his dog after he goes missing. It was released on November 19, 1993. The official tagline was "Nature created him. Science perfected him. But no one can control him."
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